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The CDC April 2021 - April 2022 provisional data shows a 7% increase from 101,167 to 108,174 of drug overdose deaths occurring in the United States
The number of drug overdose deaths involving synthetic opioids (excluding methadone; T40.4), psychostimulants with abuse potential (T43.6), and cocaine (T40.5) continued to increase compared to the previous year. Products - Vital Statistics Rapid Release - Provisional Drug Overdose Data (cdc.gov)
UPDATE 2/15/2023: The Monthly Provisional Drug Overdose Death Counts report provides estimates for the United States and jurisdictions within 4 months after the date of death. In recent months, certain states have experienced longer than usual delays in submitting drug overdose deaths. Recent trends may underestimate the death count in affected states and this potential impact should be considered when comparing results for states to previous months.
The 108,174 drug overdose deaths April 2021-2022 is 1/5th the 564,000 total from 1999-2020!
This rise in opioid overdose deaths can be outlined in three distinct waves.
Many opioid-involved overdose deaths also include other drugs
Understanding the Opioid Overdose Epidemic | Opioids | CDC